- ZIT
- Mug imperfection?
- Target for a dermatologist
- Common crisis, in middle school
- Teenage bane
- Concealer target
- Thing popped preemptively on prom night, perhaps
- Accutane target
- It's got a red head
- Red mark
- Red spot?
- Whitehead
- Popped thing
- Oily deposit
- It might give you a red nose
- It might give your cheeks some color
- Not-so-great spot for a date?
- Troubling spot
- Teenage spot?
- Something expunged from a selfie with Photoshop
- Undesirable spot
- Not-so-great red spot?
- Evidence of oil, in a sense
- Spot to pop
- Breakout "star"?
- Teen's trouble
- Clearasil target
- Teen woe
- Benzoyl peroxide target
- Face flaw
- Facial flaw
- One may pop up in high school
- This gets popped when it pops up
- Bad spot for a teenager?
- Differin target, slangily
- Bad spot for a date?
- Nightmare on prom night
- Teenager's spot?
- Unfortunate eruption
- Bad mark?
- Bad mark in high school
- Homecoming queen's nightmare
- Unwanted spot, slangily
- High schooler's bad mark?
- Teen spot?
- Blemish on the skin
- Clearasil target, slangily
- Teen trouble spot?
- Acne spot
- Spot for skin cream
- Blemish
- Not a good spot for a date?
- Pimple
- Promgoer's concern
- Skin cream target
- Teen omen
- ZENMED target
- Complexion spoiler
- Retin-A target
- Skin blemish
- Proactiv target
- Reason for adolescent angst
- Spot of acne
- First date concern
- Epidermal flaw
- Teen blemish
- Tiny source of teen angst
- Spot at the prom?
- Uncomfortable spot
- Blemish, in slang
- Minor eruption
- Teeny popper?
- Trouble spot?
- It might be right under your nose
- It's sometimes right on the nose
- Pussy thing on a puss
- Whitehead, e.g.
- Promgoer's worry
- Teen's embarrassment
- Unpopular spot
- Blemish, slangily
- Oxy-5 target
- Single outbreak
- Proactiv target, informally
- Promgoer's woe
- Accutane target, slangily
- Bit of acne, slangily
- Clearasil target, informally
- Spot concealed by makeup, maybe
- Bad mark in school?
- Embarrassing eruption
- Small blemish, in slang
- Stridex target, informally
- Temple imperfection
- Unwanted spot, in slang
- Embarrassing spot?
- Teen's facial blemish
- Bad spot for taking prom pictures
- Bit of acne, informally
- Problem before a big date, informally
- 25-Down unit
- Bit of acne
- Subject of a spot check?
- Unsightly spot
- Benzoyl peroxide target, informally
- Face difficulty?
- Temple spot, say?
- Clearasil target, in slang
- Spot on the face, informally
- Teen's woe
- Far from a popular spot
- Acne spot, informally
- Mighty Patch target
- Minor blemish
- Skin blemish, slangily
- Sore spot, perhaps
- Unwanted spot, informally
- Photo retoucher's focus, perhaps
- Target of benzoyl peroxide
- 19-Across unit
- It may be popped
- Problem for one with 26-Down
- Target of some makeup
- Acne bit
- Nose flaw
- Nose marrer
- Bad spot for a teen?
- Facial feature, sometimes
- Teen trauma
- Prom-night trauma
- Bad mark for a teen?
- Teenager's blemish
- Oxy target
- Picture day concern
- Unwanted spot
- Unwanted blemish, informally
- Complexion woe
- Teen's blemish
- Bump on the head
- Mark of a flawed kisser
- Result of a clogged pore
- Swollen skin spot
- Common spot for teens
- Stridex target
- Teenage eruption
- Pimple, informally