- PREZ
- W., once, and O now
- Title sought by Hil, Jeb, et al.
- Veep's superior
- The man
- Amtrak Joe, e.g.
- Chief exec
- Biz honcho
- Head honcho
- Leader hidden in 5-, 9-, 11-, and 34-Down, informally
- Political cartoon subject, informally
- Oval Office occupant, colloquially
- Head honcho, briefly
- Dubya, Abe, or Cal
- Barack Obama, familiarly
- Dubya, once
- Biz biggie
- Informal D.C. title
- White House resident, informally
- Ike, in the '50s
- Oval Office honcho
- U.S. head, casually
- Barry O's title
- Jack or Ike, once
- Country runner
- Informal title
- Informal leader
- Big boss, informally
- Top suit
- 122-Across, informally
- Abe or Dick
- Company VIP
- George W. or Bill, slangily
- Chief exec, in tabloids
- Head honcho, perhaps
- Company boss, for short
- Top 55 Down
- Top banana
- One in charge, informally
- Big kahuna
- Biz bigwig
- Big boss
- Big boss, briefly
- Big cheese
- Big enchilada
- Dubya's title
- Nickname of tenor saxophonist Lester Young
- Oval Office figure, familiarly
- White House sobriquet
- Country runner, familiarly
- Honor in Honduras
- 5-Down, e.g., in brief
- Head of a country, informally
- Clinton, slangily
- Hail to the Chief chief
- White House dweller, informally
- Firm honcho
- W, for one
- Bossman or bosswoman
- Abe or Ike
- W. or Bam
- W. or J.F.K.
- W., once
- Air Force One honcho
- Hil's hopeful title
- Hip hop's Dead ___
- Head of state, informally
- CIC, casually
- Commander in chief, informally
- Top exec
- Obama or Biden, informally
- USA's leader
- Oval Office VIP
- U.S. leader
- Hail to the Chief chief briefly
- Hail to the Chief guy
- Head honcho, in tabloids
- Chief exec, informally
- Selina Meyer, in some seasons of "Veep"
- W.'s ours
- Dubya, currently
- Top man, in headlines