- OPRAH
- Talk queen
- First name in talk shows
- Talk show host
- Her company is an ananym of her name
- Brilliantly colored sashimi fish (or ... host who gave 30-Down his start)
- After Neverland host
- Media mogul who played Mrs. Which in "A Wrinkle in Time"
- Interviewer of Elliot Page via greenscreen technology
- Selma costar/producer
- Big name in book clubs
- First African-American to top Entertainment Weekly's 101 Most Powerful list
- First black billionaire
- OWN owner
- Owner of the cable channel OWN
- Richest self-made woman in America
- She was recently denied a $38,000 handbag
- You get a car speaker
- One of the greatest Black philanthropists in American history
- Book club founder
- Beloved producer
- Talk show celeb
- Book booster on TV
- Book-club organizer
- Book booster
- Stedman's steady
- Mag biz "O"
- First name in talk TV
- Big name on daytime TV
- TV host Winfrey
- Talk show host Winfrey
- Noted recommender of books
- Sofia portrayer in "The Color Purple"
- Oxygen network co-founder
- Benefactor of South Africa's Leadership Academy for Girls
- Part of OWN
- Whoopi's "The Color Purple" co-star
- Beloved star Winfrey
- First name in daytime TV
- Sethe portrayer in "Beloved"
- Winfrey of "The Color Purple"
- O star?
- Big name in talk
- Competitor of Geraldo and Ricki
- Talk-show tycoon
- Alternative to Montel
- Big name in talk shows
- First name in afternoon TV
- Popular afternoon host
- Rival of Montel
- The People's Court competitor
- Celebrity with a book club
- Rival of Ricki and Jenny
- Talk show name
- Beloved actress Winfrey
- Big name in daytime TV
- Competitor of Jenny and Ricki
- Ms. Winfrey
- She helped make Dr. Phil famous
- First name in TV talk
- Daytime talk show host born in Kosciusko, Mississippi
- Big book booster
- Head of Harpo Productions
- Queen of afternoon talk shows
- The O in "O" magazine
- Book club name
- TV host who frequently features Dr. Oz
- TV talk tycoon
- Precious co-producer
- First name in afternoon talk shows
- Oxygen cofounder Winfrey
- Sofia's portrayer in "The Color Purple"
- Her talk show was based in Chicago
- Number two on Forbes's 2011 list of The World's Most Powerful Celebrities
- She produced a musical version of "The Color Purple" on Broadway
- Noted talk show retiree of 2011
- Noted talker whose name in reverse is a noted nontalker
- The O of OWN
- Media titan with a successful book club
- TV/film star whose name spelled backward is a Marx Brother
- The "O" of O magazine
- Host of the highest-rated talk show in television history
- The Butler star
- Winfrey who recently quashed a beef with Snoop Dogg
- Media mogul with her own TV network
- Montel rival
- First name in talk
- O, The __ Magazine
- TV personality with a book club
- Daytime giant
- Daytime host
- Daytime TV staple
- Daytime talk show host
- Chair of Harpo Productions
- Daytime star
- Oh! cable network co-founder
- Queen of Talk
- Star with a book club
- Day star
- Chicago-based daytime host
- Daytime TV mogul
- Talk show giant
- Talk's Winfrey
- Daytime talk star
- Popular talk show
- Star known by her first name
- Longtime talk show
- TV tycoon born in Mississippi
- Host who had a "Favorite Things" segment on her show
- Book club leader for 15 years
- Long-running talk show
- Media mogul Winfrey
- Media mogul with a Presidential Medal of Freedom
- Onetime rival of Sally Jessy
- TV book club creator
- Talk show for 25 seasons, familiarly
- Angel Network charity founder
- Personality with an online book club
- Show that had an annual "Favorite Things" segment
- Daytime TV celeb who founded Harpo Productions
- 60 Minutes part-time correspondent
- A Wrinkle in Time (2018) actress
- Dr. Phil was her frequent guest before getting his own show
- Queen Sugar co-producer
- Celeb with her "OWN" network
- Talk show host in the National Women's Hall of Fame
- Queen Sugar co-producer Winfrey
- 1994 National Women's Hall of Fame inductee
- Harpo Productions CEO
- TV host with her "OWN" network
- Winfrey of HBO's "The Immortal Life of Henrietta Lacks"
- Queen of All Media Winfrey
- Media mogul born in Mississippi
- Media mogul with a book club
- The Color Purple producer
- 2021 interviewer of Meghan and Harry
- O icon
- Host with a book club
- Harpo Productions founder
- Rosie Daley's notable employer
- Talk-show honcho
- Talk-TV magnate
- O Magazine head
- Big name in TV talk
- Chicago-based talk show
- Dr. Phil's discoverer
- TV talk host
- Winfrey of TV
- TV talk name
- Daytime megastar
- Sofia in "The Color Purple"
- The "O" of the OWN Network
- Former book-club leader
- Syndication departure of 2011
- Guest on Jay's last "Tonight Show"
- Dr. Oz Show creator
- Annie Lee in "Selma"
- OWN Network VIP
- With 45 Across, source of quote
- An executive producer of "Selma"
- Dr. Phil's mentor
- Harpo Productions boss
- Media mogul from Mississippi
- O in the OWN Network
- OWN network proprietor
- Talk host who had a satellite radio channel
- TV host with a Book Club
- OWN VIP
- Winfrey of TV talk
- She played Sofia in "The Color Purple"
- She played Sethe in "Beloved"
- Charlotte's Web costar of Cedric
- Winfrey of daytime TV
- ___ After the Show (former Oxygen program)
- Talk-show hostess Winfrey
- Talk-show hostess rivaling Phil
- ___ Winfrey (TV talk-show host)
- She comes back to Harpo
- Rival of Phil and Sally
- TV's Winfrey
- Chicago-based TV show
- Competition for Geraldo
- Competitor of Phil
- Rival of Sally
- Afternoon TV name
- Competitor of Montel
- Geraldo competitor
- Afternoon TV staple
- Big fan of Dr. Phil
- Colleague of Dr. Phil
- What "O" stands for in publishing
- Show of compassion?
- Where Dr. Phil got famous
- Chicago-based TV talk show
- Daily TV staple since 1986
- First name in daytime talk
- Friend of Dr. Phil
- Longtime staple of daytime TV
- Show taped at Chicago's Harpo Studios
- First name in book clubs
- Winfrey who said "I still have my feet on the ground, I just wear better shoes"
- Co-producer of the film "Precious"
- Long-running hit TV show based in Chicago
- Player of Sethe in "Beloved"
- Hit TV show that ended in 2011
- What "O" stands for in the magazine business
- Media icon with an eponymous Starbucks beverage
- Voice actress in Disney's "The Princess and the Frog"
- What "O" on a newsstand stands for
- Actress in "Selma," familiarly
- O, The ___ Magazine
- Celeb parodied by Maya Rudolph on "S.N.L."
- O of the magazine world
- She's got her OWN network
- Show on which Dr. Phil became famous, familiarly
- TV personality with the best seller "What I Know for Sure"
- She played Annie Lee in "Selma"
- The "O" in television's OWN
- The "O" of the magazine O
- Who said "I'm black. I don't feel burdened by it .... It's part of who I am. It does not define me"
- Entertainer Marx / Entertainer Winfrey
- Founder of Harpo Productions
- She played Mrs. Which in 2018's "A Wrinkle in Time"
- What the "O" of O magazine stands for
- Book club leader on TV
- Host of an Apple TV+ book club
- Talk show queen named after a figure in Ruth
- High-profile interviewer of Harry and Meghan
- Noted book club leader
- Author of "What I Know for Sure," familiarly
- Celeb with a good friend named Gayle
- Co-host of the 1970s program "People Are Talking"
- First Black female billionaire, informally
- Big name in media and philanthropy
- Highest-rated daytime talk show in American history
- Longtime show host known as the "Queen of All Media"
- Media mogul whose production company is her name in reverse
- One-named "Queen of All Media"
- Celebrity whose middle name is Gail, appropriately enough
- Portrayer of Mrs. Which in 2018's "A Wrinkle in Time"
- Talk show host nominated for an Academy Award
- Who cries "You get a car, you get a car!" in a viral meme
- Her full name anagrams to "horny rap wife"
- Mississippi-born TV mogul
- Book Club oligarch
- Winfrey of 'Beloved'
- What "O" stands for in a checkout line
- No. 354 of the Forbes 400
- No. 286, 47 years old, $900 million, single, Chicago, television
- She interviewed both George and Al in 2000
- The next president, according to a probably joking George W. Bush
- George and Al were both interviewed by her
- Winfrey in "Beloved"
- Talk-show queen
- Mrs. Which player in 2018's "A Wrinkle in Time"
- O Magazine's O
- Super Soul Sunday host
- The "O" in OWN
- Harpo Productions founder, familiarly
- The Color Purple star
- Daytime talker
- Noted book reader
- O founder
- Popular TV star
- Producer, actress and host
- Beloved Winfrey
- Beloved name
- Big name on TV
- Big-time talker
- Bookish hostess
- Star of TV talk
- Queen of talk shows
- Noted book promoter
- The "O" in magazines
- First name of a "The Color Purple" cast member
- Billionaire into books
- Namesake of OWN
- Media mogul with a noted book club
- Notable book club maven
- The "O" of TV's OWN
- Everybody gets a car! TV host
- Billionaire with a book club
- TV host ... or, read backward, a Marx brother
- *Bright fish used in sushi
- Host of a talk show that aired from 1986 to 2011
- Winfrey with a book club
- Afternoon TV mainstay
- Gabmistress Winfrey
- She's known for a gift of gab
- Winfrey
- TV personality
- Famed dieter
- Celeb on Forbes' billionaire list
- Big name in TV
- Billionaire talker
- Dr. Phil's benefactor
- Celeb with a magazine
- Star on O Magazine covers
- TV mogul Winfrey
- Winfrey who played Deborah Lacks
- Winfrey who starred in "Beloved"
- Harpo Productions founder Winfrey
- Super Soul Sunday host Winfrey
- Celebrity with an annual list of Favorite Things
- First name at Harpo Productions
- Host to Dr. Oz
- Precious co-producer, familiarly
- What Happened to You? co-author Winfrey
- She voiced Eudora in "The Princess and the Frog"
- What I Know for Sure author
- Number 1 on Entertainment Weekly's 1998 power list
- Celeb with a book club
- Celeb with her own TV network
- Celeb with a TV network
- Star with a 10% stake in Weight Watchers
- Queen of All Media
- Barack awarded her the Presidential Medal of Freedom
- Rumored 2020 presidential candidate
- Star with an "Angel Network" charity
- A Wrinkle in Time co-star
- She co-starred with Whoopi in "The Color Purple"
- She was awarded the Presidential Medal of Freedom by Barack
- Barack gave her the Presidential Medal of Freedom in 2013
- She has her OWN network
- You get a car, and you get a car! speaker
- Media mogul with an annual Favorite Things compilation
- Winner of the first humanitarian Emmy
