- LOCO
- In __ parentis
- Insane
- Weed or motive starter
- In ___ parentis
- Plumb crazy
- Spanish nuts?
- El Pollo ___ (Mexican fast food chain)
- Touched
- Batshit
- Crazy
- Crazy in the coconut
- Off one's trolley
- Crazy, in Texas
- Bats
- Bonkers
- Crackers or nuts
- Bananas
- Haywire
- Not all there
- Nutty
- Touched a bit
- Like an unreasonable idea
- Out of one's gourd
- Prefix with weed or motion
- Bats or bonkers
- Off your rocker
- Crackers
- Off one's rocker
- Crazy, in Cozumel
- In ___ parentis (acting as mom or pop)
- Cuckoo
- Bananas, nuts, or crackers
- Crazy in la cabeza
- Cuckoo, in Cancún
- Wacky
- Mad
- Crazy, in Cancún
- Mad, in Madrid
- Off the deep end
- Nuts
- Unglued
- Batty
- Nutty as a fruitcake
- Kind of weed
- Nutty^LOC
- See 20 Across
- Berserk
- In ___ parentis: acting as a parent
- Touched in the head
- Crazy as a loon
- Screwy
- Daffy
- Nuts or crackers?
- Off one's rocker, and a hint to what the four longest puzzle answers have in common
- Not right in the head
- Caracas crackers?
- Daft
- Maniacal
- Prefix for an intoxicating weed
- El Pollo __: southwestern restaurant chain
- Like un maníaco
- El Pollo __: chain in the U.S. and Mexico
- Not of sound mind
- Un Poco __: song from "Coco"
- Wacky, to Juan
- Batty, in Bolivia
- Goofy
- Off the wall
- Plumb __
- Kooky
- Plumb __ (daffy)
- In a frenzy
- Frenzied
- Prefix for motion
- Coco __ (rum cocktail)
- Pliny's place
- Prefix for motive
- Making no sense
- Nero's place
- Buggy
- Cracked
- Wacky, in Oaxaca
- Meshuga
- Poisonous plant.
- Crazy: Slang.
- Poisonous plant of Southwest.
- Poison plant of bean family.
- Crazy: Colloq.
- Slightly crazy.
- Poisonous weed.
- ___ citato (in the place quoted): Lat.
- From place to place: Comb. form.
- ___ citato.
- Kind of Western weed.
- From place to place: Prefix.
- Western weed.
- Place: It.
- Place: Prefix.
- Prefix with motion or motive.
- Weed of the prairies.
- A kind of motive.
- Frenzied: Slang.
- Part of a train, for short
- Noxious weed
- Weed of Southwest
- Crazy, in Córdoba
- Disease of livestock
- Crazed
- Gone bonkers
- Like a crazy hombre
- Word form with motive
- Like a kook
- Having bats in the belfry
- Loony
- Pixilated
- Motive leader
- In ____ parentis
- In _____ parentis
- As written, in music
- Cockeyed
- Unhinged
- Over the edge, so to speak
- Nutso
- Tetched in the head
- In ___ parentis (legal doctrine)
- Lead-in to motion
- More than a little off
- Plain crazy
- Gonzo
- Stark raving mad
- Totally baked
- Way off
- Wacko
- Unscrewed
- Crazy, in Spanish
- ___ citato (in the passage quoted)
- Cray cray
- In ___ parentis (legal term)
- Do the ___-motion ... (Grand Funk Railroad)
- The ___-Motion (Grand Funk Railroad)
- Kylie Minogue "The ___-Motion"
- 32 Down, another way
- Nuts, in Nogales
- Out of one's head
- Disease that affects livestock
- El Pollo ___ (restaurant chain)
- Little Eva's "The ___-Motion"
- Un Poco ___ (song from Pixar's "Coco")
- Motion starter
- Nuts or crackers, take your pick
- Musical direction
- 'Round the bend
- Out in left field
- Quite mad
- Batty or bonkers
- Cuckoo, in Cancun
- Motive starter?
- Out of one's ever-lovin' mind
- Crazy in Cancun
- Crazy in Spain
- Out of one's mind
- Batty, in Mexico
- Batty, in Spain
- Not mentally sound, in Seville
- Batty, south of the border
- Nuts or bananas
- Nuts, in Spain
- Crazy in Chihuahua
- Crazy, down south
- More than eccentric
- Crazy, in Veracruz
- Off the beam
- Not sound, in Seville
- ___foco: old pol
- Off in the head
- Belonging in a bughouse
- ___ moco (rhyming Hawaiian dish)
- Completely bananas
- Around the bend
- Wacky as can be
- Bananas or nuts
- Wacky, in Mexico
- Wacky, south of the border
- Nutty, slangily
- Totally unhinged
- El Pollo ___
- 17 Crackers
- Bughouse
- Coco ___ (rhyming cocktail)
- Bananas or crackers
