Crossword clues for Very significant:HOWMOODYPARTNERCan I get a vibe check from my significant other?PETRIDish with cultural significance?NALASimba's significant otherAEONSignificant stretchNOTABENEMark of significanceOTHERSSome are significantINANEWithout significanceERASignificant stretchHEFTSignificanceERASignificant periodERASSignificant stretchesGFSSome significant others, in IMsMERERLess significantOFNO___ significancePEONPerson of no significanceSLICINGINTOSignificantly diminishing, as profitsSMALLERLess significantGREATERMore significantERASignificant yearsIMPORTSignificanceABOMBSignificant source of falloutEVALUATEDetermine the significance ofGANGESSignificant river to HindusIDLEOf no significanceCLIFFSignificant drop-offFLAGMark as significantRASTAOne for whom dreadlocks carry religious significanceGDPSignificant econ. indicatorRANDEEPHad significant rootsATONSignificantlyBAEDarlin', in significantly more updated slangGIANTSTEPSignificant bit of progressELATEBrighten significantlyEONSignificant stretchPTSDAffliction for which 17-Down are at significant riskNOENDVery significantlyEONSSpans over significant lengthsACTIONCARDTurn or river that causes significant betting between at least two players, in Texas hold 'emDCUPProvider of significant supportONTHEMAPSignificant enoughORCAOne responsible for significant breachesBIGJOBSignificant undertakingSTEROIDERABonds played a significant part in itEONSVery significant stretchONEWith 45-Down, not a significant quantityLESSNot so significantBCUPAverage American woman's need in 1983 (it's changed... significantly since then)HUGEQuite significantSSNIts first three digits had geographic significance until 2011: Abbr.HUBBYSignificant other