Crossword clues for The E in E. S. T. 7 letters:REFRAINE-I-E-I-O, e.g.EMANUELThe "E" in Alfred E. SmithEASTERNThe E in E. S. T.REFRAINE-I-E-I-O, sayREFRAINE-I-E-I-O, for oneITSCOLDI'm fre-e-e-zing!MCMAHONHe-e-e-ere's Johnny! sayerSMILEYSE-mail grinsSMILEYSHappy e-mail symbolsHOARDERCompulsive subject of a former A&E seriesALIBABAChinese e-commerce company with a record-setting 2014 IPOROBBASEPartner of DJ E-Z Rock on the 1988 hip-hop classic "It Takes Two"TELEXEDSent a message, before E-mailEMANUELThe "E" in C.P.E. BachONEDIMEWords under "E PLURIBUS UNUM"WEBPAGEE-tailer's creationVITAMINA, B, C, D, E, or KSPAMMEDSent junk e-mail toNICETRYYou get an E for effortTHESOUPE! series hosted by Joel McHalePOSTAGEE-mailer's non-needSPAMBOTJunk e-mail senderOPTEDINChose to participate, as with an e-mail listOHGOODYJust gre-e-eat...DRIPTIPRhyming e-cigarette extension that facilitates pouring the flavor liquid into the cartridgeNISSANZJapanese sports car akin to the Jaguar E-TypeEYEEXAMIt often starts with an "E"PDFDOCSThey may require e-signatures, informallyRAGTIMEE. L. Doctorow novelSCANDALFrequent subject of "The E! True Hollywood Story"INITIALAlfred E. Neuman has oneRHYTHMSLongest word not containing an a, e, i, o, or uOCTETTEMendelssohn work in E-flat major, in FrenchBALLPITChuck E. Cheese's fixtureACROBATPopular e-readerEYEEXAME F P T O Z visitWRITETOE-mailCOYOTESWile E. et al.MODESTOCalifornia home for E & J Gallo WineryREPLIESSends a follow-up e-mailSLYNESSWile that fails Wile E.PORSCHEPanamera S E-Hybrid makerSPAMBOTAutomated junk e-mail senderISAIDNOReply to "Aww, Mom, ple-e-ease?"BEATBOX*Imitate Doug E. FreshTELEXESOutmoded e-mailBACILLISalmonella and E. coli, e.g.TRIVIAL(With 38 Across) Test subject #3 perceives G as blue, E as pink, H as yellow; maybe he likes to play ...IAMCAITE! documentary series about a very public transitionSCEPTERRemix of 37-Across (ft. Ben E. King, Queen Latifah, and Prince)?