Crossword clues for S. African Prime Minister. 5 letters:BOTHAFormer South African prime minister P.W.BOTHALouis or P.W., the first and last South African prime ministersMALANS. African Prime Minister.SMUTSWW II South African prime ministerSMUTSSouth African prime minister JanSMUTSTwo-time South African prime ministerJANSMUTSSouth African prime minister who promoted Boer-British cooperation