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% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)

Crossword clues for Major League, in slang:

BIGS: Major leagues (slang)
BIGTIME: Major-league baseball: Slang.
BIGS: Major leagues, in slang
BIGS: Major League, in slang
BIGS: Major leagues, in baseball slang
THE: With 29-Across, baseball's major leagues, in slang