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% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)

Crossword clues for Long-run TV hit 4 letters:

MASH: Long-running TV hit
MASH: Long-run TV hit
OPRAH: Long-running hit TV show based in Chicago
GENERALHOSPITAL: Long-running TV hit beginning 4/1/63