Crossword clues for It is its last letter 5 letters:THETAIts last three letters are another Greek letterCHLOEWoman's name often written with two dots above the last letterSUITEOne might have three parts, with or without its last letterOMEGAAchilles' last letterOMEGAAristotle's last letterMABELName that becomes a bygone conglomerate when its last letter is doubledOMEGALast letter from GreeceCHINOTrousers material that becomes a country by changing its last letterANDREMan's name whose last letter often has an accentOMEGALast letter of Greek alphabet.OMEGALast letterNSYNCBand named for the last letters of the first names of its original membersOMEGALast letter of the Greek alphabetOMEGALast letter, in AthensOMEGALast letter in the Greek alphabetSHARDItem that can be described by changing its last letter to a PXXXXXLast letterCOCOAHot drink with a silent last letterOMEGALast letter to AristotleNIGELMan's name that's an African country if you change the last letterBIORESkin-care brand with an accent over its last letterOMEGALycurgus's last letterAITCHIt is its last letterVIOLAIt becomes its slightly smaller cousin when its last letter is changed to "in"NOTRE___ Dame (Note the last 2 letters of this answer + ...)DEFIBBroken heart remedy, briefly? (last 3 letters + ...)BRAVOWell done! (Last 2 letters + ...)MOUTHPlace for gum and gums (last 2 letters ...)MILERDistance runner who aptly crosses the last 4 letters of 64-AcrossSOUSAMarch composer whose name's last three letters are aptARROWSharp projectile that aptly crosses the last 6 letters of 16-AcrossASEANEconomic org. of which Indonesia and Thailand are charter members (and whose last four letters are a man's name)MARINEntertainer Cheech (last 3 letters ...)ICANTSorry, too busy (In this clue's answer, note the last 3 letters + the first 3 of 21-Across)NEVERWith 39-Across and 49-Across, rule broken by the three theme entries' first and last two lettersTUNISCapital city whose name is its country minus its last two lettersPESCIHome Alone co-star Joe (Last 3 letters + the start of 47-Across)OMEGALast Greek letterARLESFrench city whose last two letters are silentDECORInterior design (Last 3 letters + 1 above the block + ...)TUNISCapital city whose name is its country's name minus its last two lettersSOUSAThe last three letters of his name are very apt, considering his most famous pieceOHARAHer name and her plantation's share the same last 3 lettersSEVENNumber that's odd, despite its last four lettersOMEGALast of 24 lettersALPHAGreek letter (definitely not the last one)KLINEActor Kevin whose last name shares four letters with his firstOMEGAGreek letter used to denote the last entry in a seriesTRULYLast word of a business letter.ZETASSixth letters that look like they should be last