Crossword clues for It can be a headache 8 letters:HEADACHEMajor problemHEADACHEMajor annoyanceHEADACHEIt's a real pain!HEADACHEProblemHEADACHECause of trouble: Colloq.HEADACHEBothersome personHEADACHEBig painHEADACHESource of worryHEADACHEAnnoyanceHEADACHEAspirin targetHEADACHEMajor inconvenienceHEADACHEPain in the butt, ironicallyHEADACHEBig botherHEADACHEAnnoying person or situationHEADACHEVexatious problemHEADACHEAcute problemHEADACHEPain in the brainHEADACHEIbuprofen targetHEADACHENuisanceHEADACHEAny vexing problem: Colloq.HEADACHEAnnoying situationHEADACHEOne reason for taking aspirinHEADACHEBothersome typeHEADACHEPain in the buttHEADACHEBig problemASPIRINSHeadache stoppersTYLENOLSThey help headachesDULLPAINSlight headache, maybeHANGOVERIt can be a headacheMIGRAINEHorrible headacheHANGOVERPost-bender headacheOVERBOOKWhat airlines sometimes do, causing headachesNUISANCEHeadacheOHBOTHERSuch a headache!SANDTRAPWoods' headacheMIGRAINEKind of headacheMIGRAINEThrobbing headacheFLATTIREMotorists' headache.MIGRAINENervous headache.STTERESAPatron of headache sufferersMIGRAINEHeadache.BREAKAGEChina-shop headacheMIGRAINESplitting headache.FINANCESCommon causes of headaches.PROTOCOLWashington hostess' headache.LAYOVERSTerminal headaches?FEVERFEWPlant used as an herbal remedy for headachesFEVERFEWPlant used in herbal medicine to treat headachesFLATTIREDriver's headacheDIVORCEEOne with a splitting headache?