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% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)

Crossword clues for It can be a headache:

HEADACHE: Source of worry
HEADACHE: Worry
HEADACHE: Bothersome type
HEADACHE: Cause of trouble: Colloq.
HEADACHES: Major nuisances
HEADACHE: Nuisance
HEADACHE: Inconvenience
HEADACHE: It's a real pain!
HEADACHE: Major annoyance
HEADACHE: Vexatious problem
HEADACHE: Bother
HEADACHE: Big pain
HEADACHE: Annoying situation
HEADACHES: Brain storms.
HEADACHE: Cephalalgia
HEADACHES: Annoying situations
HEADACHE: Problem
HEADACHE: One reason for taking aspirin
HEADACHE: Acute problem
HEADACHES: Hassles
HEADACHE: Major problem
HEADACHE: Something treated by Tylenol
HEADACHE: Big bother
HEADACHE: Ibuprofen target
HEADACHES: Problems
HEADACHE: Annoying person or situation
HEADACHE: Pain in the butt
HEADACHE: Big problem
HEADACHE: Migraine
HEADACHE: Annoyance
HEADACHE: Aspirin target
HEADACHE: Bothersome person
HEADACHE: Major inconvenience
HEADACHES: Troubles
INLAW: Wedding planner's headache, perhaps
IMP: Sitter's headache
DELAY: Subway headache
GOUT: Joint headache
RECALLS: Auto dealer's headaches
PITAPOCKET: Pants storage that causes constant headaches?
LAG: Streaming headache
LIE: Fact-checker's headache
EXES: Headaches at some wedding reception table placements
STRESS: Headache cause
FLAT: Motorist's headache
RECALL: Auto manufacturer's headache
SPLIT: Kegler's headache
ROUGHSEAS: Helmsman's headache
PILL: Headache relief, perhaps
SEATING: Wedding reception planner's headache