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% replaces any number of letters (la% - lake, lamp)_ replaces one letter (ca_ - car, cat)

Crossword clues for $50 portrait:

GRANT: $50 portrait
JFK: 50-cent portrait
USGRANT: 50's portrait?
WREN: Former 50-pound note portrait
GRANT: His portrait is worth $50
GRANT: His portrait's on the $50 bill